The strongly-fancied Practical Move has passed away of a "suspected cardiac event" during work at Santa Anita as he prepared for a tilt at the Breeders' Cup Dirt Mile on Saturday.

The Tim Yakteen-trained three-year-old had just Cody's Wish ahead of him in the betting following his impressive win in the Santa Anita Derby in April.

A statement posted on www.breederscup.com said: "Breeders' Cup is saddened to report the loss of Practical Move after what is suspected to be a cardiac event while returning from his gallop this morning at Santa Anita Park.

"His rider was uninjured, and the horse was immediately tended to by veterinarians from the California Horse Racing Board (CHRB), 1/ST Racing, and Breeders' Cup.

"Every year, Breeders' Cup works closely with its host track, state racing commission, and the Horseracing Integrity and Safety Authority (HISA) in the lead-up to the World Championships to implement stringent safety and integrity protocols.

"These processes are in place to protect the wellbeing of our human and equine athletes, and Breeders' Cup is committed to continuously improving the ecosystem of care surrounding every horse."