A spate of injuries has hit the England team ahead of their friendly against the Socceroos, forcing coach Roy Hodgson to adjust his line-up.
The Socceroos are set to face a vastly under-strength England in Sunderland after injuries forced Roy Hodgson to drastically alter his team.
Just two weeks out from his first European Championship game, the England coach has been hit with a spate of injuries to his 26-man squad.
Australia coach Ange Postecoglou meanwhile has a fully fit group of 23 to choose from, most of whom are expected to feature at some point in Friday night's game (Saturday AEST).
Manchester United young gun Marcus Rashford will debut against Australia, likely in the starting 11 in place of Daniel Sturridge who hasn't trained for the last two days with a calf injury.
England will make a game day decision on whether or not the Liverpool striker plays.
Defender Gary Cahill has been ruled out entirely after requiring an injection to his hip, but should be fit next week ahead of England's last friendly against Portugal.
And midfielder Fabian Delph didn't even travel with his England teammates on Thursday, left behind in Manchester to nurse a groin strain which will likely cost him a spot in Hodgson's final 23-man Euro squad to be named this weekend.
"If Sturridge isn't fit tomorrow then I think you'll all work out that he [Rashford] is going to start the game," Hodgson said in England's pre-match press conference.
"I'm happy with that, I'm more than content he can handle the situation.
"It doesn't take a lot of detective work to work out that, with me wanting to rest [Jamie] Vardy and [Harry] Kane," Hodgson said.
"There was no doubt that my original intention was to choose between Sturridge, Rashford and possibly one other."
Hodgson had been toying with the idea of a front three against Australia featuring captain Wayne Rooney on the left, Adam Lallana on the right and either Sturridge or Rashford in the middle.
But his formation looks set to change now to accommodate his depleted forward stocks, with Rooney likely to now start from the bench.
With Cahill out, Liverpool midfielder Jordan Henderson looks the man to take the captain's armband.
Fellow Liverpool man Nathaniel Clyne should line up at right back with Ryan Bertrand on the left, and Fraser Forster will replace Joe Hart in goal.
Postecoglou refused to give any hints into the make-up of his starting 11, but A-League sharpshooter Jamie Maclaren is expected to debut up forward.
Milos Degenek, Stefan Mauk and Brad Inman also look set to make their international debuts.
Australia hasn't played England since a memorable 3-1 victory at Upton Park in 2003 when Harry Kewell, Tony Popovich and Brett Emerton scored the goals.
Socceroos captain Mile Jedinak remembers the game, but said it hadn't been spoken about in camp this week.
"We all know it, I definitely do, I'm sure most of the other boys do but the sole focus is going to be on what we're trying to do," Jedinak said.
"It's a great honour to be here and to be representing my country.
"If we can test ourselves against good opposition, away from home, it's going to put us in a good place going forward."
Australia possible starting XI: Mathew Ryan; Josh Risdon, Milos Degenek, Bailey Wright, Brad Smith; Mile Jedinak; Aaron Mooy, Tom Rogic; Robbie Kruse, Matt Massimo Luongo; Tomi Juric England possible starting XI: Fraser Forster; Nathaniel Clyne, John Stones, Chris Smalling, Ryan Bertrand; Jordan Henderson, Jack Wilshere, Andros Townsend, Ross Barkley; Marcus Rashford, Adam Lallana.
